My Current Supplement List
- Probiotic Muti-Enzyme Digestive formula
Super B Complex
Pantethine (600-900 mg daily)
L-Carnitine 500 mg
DHEA & Pregnenolone Complex (each cap = DHEA 10mg, pregnenolone 15 mg)
Vitamin D3 (5,000 iu)
Coral Calcium (400 mg)
Vitamin E (400 iu)
I probably need a good multivitamin. What else is missing ?
Pic of my order
HCG Phase 2 (VLCD - 500 calorie days)
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Leptin Reset
Supplements Recommended
1. Pinolenic Acid: .
2. Pycnogenol: inhibits key triggers of inflammation..
3. Green Tea extract:
4. Kelp:
5. CLA:
6. Curcumin:
7. Resveratrol:
8. Pregnenolone:
9. Vitamin E:
10. Chromium picolinate:
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1. Pinolenic Acid: Recent research has shown its potential use in weight loss by curbing the appetite. Pinolenic acid causes the triggering of two hunger suppressants—cholecystokinin and glucagon-like peptide-1 (GLP-1). Pinolenic acid may have LDL-lowering properties by enhancing hepatic LDL uptake. Cholecystokinin is recognized to suppress appetite in humans. When a partially digested meal rich in fats or proteins leaves the stomach to enter the duodenum (the first portion of the small intestine), the duodenal mucosa cells secrete CCK. In turn, CCK stimulates the pancreas to secrete numerous enzymes to help digest food. CCK also acts on the gallbladder to stimulate the release of bile into the small intestine, which helps to emulsify and break down fats. Most important to appetite control, CCK acts to slow gastric emptying and to promote a feeling of fullness, thus suppressing further food intake. Glucagon-like peptide-1 is another hormone that is intimately connected with fullness and satiety. Produced in the small intestine in response to fat and carbohydrates, GLP-1 works in part by activating the “ileal brake” mechanism. This slows down the absorption of food in the gut, promoting feelings of fullness and satiety, and therefore limits the desire for further food intake. GLP-1 also helps to control the health of pancreatic beta cells, which serve the crucial function of manufacturing insulin in the body. Abnormal beta-cell function plays a key role in the development of insulin resistance due to intracellular Magnesium deficiency , and scientists believe that therapies that boost GLP-1 levels could help to favorably alter the course of diabetes.
CCK and GLP-1 are key hormones for appetite control and satiety, and scientific studies show that these two hormones exert effects in combination that are more powerful than either alone (synergistic effects). Studies of normal-weight and obese subjects have shown that GLP-1 and CCK reduce feelings of hunger and decrease voluntary food intake at meals.
2. Pycnogenol: inhibits key triggers of inflammation. In 2000, it was first discerned that Pycnogenol works on a genetic level by suppressing activation of a genetic master switch, called nuclear factor-kappa B, which regulates expression of more than 300 genes that promote an abnormal inflammatory response. In a 2006 study on seven healthy human volunteers, 200 milligrams a day exerted anti-inflammatory effects, apparently by inhibiting pro-inflammatory gene expression. It is a potent blocker of series two prostaglandins (excessive omega 6) that can cause leptin resistance to develop at the SOCS3 receptor site of leptin in the brain.
Pycnogenol boasts more than 220 published studies over the past 35 years. In 2008 alone there were three published studies in the peer-reviewed literature for osteoarthritis. In one, 100 milligrams per day of the ingredient decreased the use of anti-inflammatory drugs by 58 percent (which led to a 63 percent decrease in gastrointestinal irritation, versus no change in the placebo group), lowered levels of HS-CRP, cut patient pain and increased patient walking distance. This is a drug I use myself because of my knee injury.
On the cardio front, it specifically enhances circulation, reduces cholesterol, controls blood pressure and protects against heart infarction and stroke. In one study amongst people with borderline hypertension, eight weeks of taking Pycnogenol led to diastolic blood pressure dropping from 139.9 to 132.7.
3. Green Tea extract: Green tea extract boosts the “resting” metabolism by inhibiting an enzyme called catechol-O-methyl transferase (COMT) that breaks down norepinephrine, an adrenaline-like hormone that sustains energy production. This action helps to burn more calories for fat loss. HCG is a low calorie diet that uses hypothalamic modification to try to increase weight loss. In a large clinical trial, a patented green tea phytosome extract produced exceptional weight loss in obese individuals. Supplemented subjects lost almost 31 lbs over 3 months, while controls lost just 11 pounds! Both groups followed a low calorie diet. This study is particularly interesting for HCG patients. Green Tea is also loaded with ECCG a potent antioxidant that is also a potent aromatase inhibitor. This keeps the sex steroid hormones at a higher level supporting HDL levels in the liver to improve endotoxin clearance and decrease plasma oxidative potential (sdLDL). Green Tea also slows down the effect of the enzyme lipase in the gut. This helps slow the absorption of fats. I drink on average close to 1-1.5 liters of green/black tea daily with coconut oil melted in it.
4. Kelp: is potent inhibitor of amylase and another digestive enzyme called alpha-glucosidase. It also lowers BG and it helps thyroid function by increasing dietary Iodine levels.
5. CLA (3.4 g/day) : is found in grass fed meats and raw dairy products. A study that showed a dose of 3.4 g CLA per day for 12 weeks seems to be sufficient to reduce body fat mass (BFM) significantly in overweight and obese humans
6. Curcumin: The active compounds in turmeric known as curcuminoids are potent phytonutrients that contain powerful antioxidant properties, showing activity as much as 300 times greater than that of vitamin E. The main curcuminoid, Curcumin helps to counteract the damaging effects of free radicals in the body, exerting extraordinary liver protection to aid in weight loss lowering IL6 and TNF alpha. I really like curcumin when it is mixed with raw black pepper in cooking because it increases its effectiveness by ten fold when taken in tandem. This powerfully lowers your HS CRP and serum ferritin levels. I use this in supplement form myself and use the spice turmeric on just about every meal I eat.
7. Resveratrol: increases mitochondrial biogenesis leading to increased exercise endurance and protection from diet induced obesity. Resveratrol increases SIRT 1 and has wide effects all over the our genome. It activates many epigenetic switches that control fat and protein metabolism favorable for weight loss. Resveratrol effects were shown to be mediated through the SIRT1 gene and mTor pathways and PGC-1a pathways. Many people who are LR complain of losing muscle mass while on the HCG diet. This is because they are profoundly LR and they are not stimulating the AMPk pathway because of how the diet is constructed. Resveratrol helps modulate this when calorie reduction is occurring. Anyone who is a neurosurgical patient of mine or a FB friend already knows how I feel about Resveratrol. I take large amounts this supplement myself because of the myriad of good things it does to our biology. In a recent study from the American Journal of Clinical Nutrition , resveratrol was shown to: inhibit preadipocyte proliferation inhibits preadipocytes’ maturation into mature adipocytes stimulates glucose uptake inhibits de novo lipogenesis cause a down regulation of the inflammatory cytokines IL-6, TNF-alpha, NF-kB, and IL-8 (IL-8 is proatherogenic- enhances CAD) Resveratrol increases production of rhBMP2 to increase bone mass which is important for leptin resistant patients with obesity, high cortisol levels or those with anorexia.
8. Pregnenolone: replacement to support poor steroid genesis that is common in HCG users. Pregnenolone falls dramatically in two states. Aging and in leptin resistance. The fall in LR is due to excessive sympathetic outflow from the the brain due to stress. This stress often translates to increase amounts of adrenal fatigue seen in these patients. If you remember my Hormone 101 blog I said there that LR leads to adrenal resistance given enough time. Pregnenolone converts into DHEA and progesterone. DHEA does not convert into progesterone, rather it converts into estrogen and testosterone. It can also convert to cortisol as well so this dose needs to be done with salivary levels and the care of your doctor. Without context you can make some errors in dosing.
9. Vitamin E: Is useful in preventing lipid peroxidation. Fats are very sensitive to oxidation and this is the antidote to this. Its major effects for weight loss are in being a powerful reducer of HS CRP which reduces many of the inflammatory cytokines associated with leptin resistance development. For those who have been on multiple rounds of HCG I also think adding high dose alpha lipoid acid is prudent to this regimen as well. I usually will have multi rounders use 600 mgs three times a day.
10. Chromium picolinate: works by increasing peripheral tissue to insulin. This allows for more AMPk pathway signaling that increases your body composition as you lose weight. Some claim it curbs appetite but I do not find this to be a major benefit. It also is very helpful in shredding weight when it is used with coconut oil and Vitamin K2. This is a method that body builders also use. If you are new to HCG then you can get away with 200 mcgs a day but if you are a frequent user of HCG I would use that dose three times a day. Chromium is synergistic when used with L-arabinose. It is a non absorbable sugar the blocks sucrase digestion and works quite well when paired with chromium to lower blood sugars and HbA1c.
********All HCG users should seriously consider high dose PQQ use while using HCG (not homeopathic HCG)
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